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When marketing spin gets in the way of facts and skews results with jargon and overinflated findings, nobody wins, and it’s ironically not a smart move for Alpha Brain

Although it has been featured in many news media outlets, and it’s definitely been discussed countless times in the Joe Rogan Experience Podcast (of course, it’s his own product), the cognitive enhancement drug’s effectiveness has often been examined and scrutinized by the nootropic community. Even though Alpha Brain has had clinical trials boasting great improvements to memory and cognition in comparison to placebo, these trials fall short of nothing more than marketing ploys and improper testing.

Alpha Brain may be an effective tool for improving cognitive skills just like every other nootropic stack these days, but how much of a competitive edge does it actually give you? Four specific ingredients: Vinpocetine, Vitamin B6, huperzine-a and alpha GPC. These work in a multitude of different ways in order to improve cholinergic functioning and short term memory recall. Although, this is only really beneficial in people with diets that have very little to no sufficient cholinergic intake (vegetarians, vegans, or those who steer clear of meat or eggs). As for the vitamin B6, those who suffer from nutrient intake defficencies may find great utility aswell.(this differs for everyone along with required RDI, and those who suffer from the Pyrrole Disorder – Pyroluria).

Alpha Brain is one of the few nootropic blends that has had clinical trials with some “success”. A 2015 Boston University study in the Journal of Human Psychopharmacology showed significant findings in favor of Alpha Brain including :

  • 12% verbal recall improvement (compared to placebo)
  • 21% faster completion time (measured by executive function assessment compared to baseline)
  • As safe and tolerable as placebo

Although it is worth noting that is clinical study was far from perfect, with only an embarrassing 60 test subjects in the sample with no recorded demographics of them such as age, race, genetics & diet. This study should be taken with a grain of salt and further investigated as Analysis of variance (ANOVA) was used for metrics, without the collection of supporting demographics from the sample size. The findings of this study were published as “significant improvement” with an average ANOVA score of ~0.06. An ANOVA test considers a small effect size 0.10, medium being 0.25, and large 0.40. An ANOVA test presumes the test demographics and variables are all the same in testing (this is impossible as everyone is different).

So all round, in conclusion, more studies need to be done. This one wasn’t great at all. Don’t believe something because it’s passed a clinical trial or two, effective clinical studies require a number of variables and constants to be recorded, a much bigger sample size than just 60 patients, and proper metric systems designed for that particular study should be used when identifying test markers, limits and most importantly the difference in metric measurement and findings in results need to make it crystal clear exactly how much more efficacious it is compared to the control, how the study could be improved next time, and if the findings actually show viable support for the hypothesis in real-world terminology and application. There’s no point in investing in an overpriced supplement if the improvements it can bring can also be easily achieved with a few tweaks to your diet.


Too Long Didn’t Read?:

don’t bother with alpha brain until you get yourself checked by a doctor on your Pyrrole synthesis levels, eat more choline-rich foods like red meat or eggs, and if you suffer from Pyrrole Disease, supplement yourself daily with vitamin B6 and Zinc! Also, if you wish to request more vendors to become a part of our trusted program, where we put them through the ropes to ensure quality and purity is met! you can nominate vendors and find out more here!